Functional Brain Receptor Imaging with Positron Emission Tomography

Functional Brain Receptor Imaging with Positron Emission Tomography

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A new copyright derivative for imaging the Boys Polo dopamine transporter has been developed.Measurements of radioligand binding of 11C-(+)-McN-5652 in vivo with PET suggests that ecstasy interacts directly with the serotonin reuptake sites and that a single oral dose of ecstasy (1.5 mg/kg) does not cause any changes in the serotonin transporter density in the human brain.Finally, a number of epibatidine derivatives have been developed as ligands to study the central nAChRs in vivo, however, toxicity studies Underwear prevented further clinical use.